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Sometimes, its as simple as diet

That is an issue because a dehydrated athlete will have more concentrated urine relative to a well-hydrated athlete, and so the concentration of any substances (prohibited or not) appearing in their urine will be higher, thus increasing the probability of an anti-doping rule violation being pursued against them simply because of their hydration status

For instance, sodium butyrate intake was reported to reduce PD-related motor symptoms via mechanisms associated with gut microbial dysbiosis regulation 43 , intestinal barrier protection through the activation of G-protein-coupled receptor 109 A (GPR109A) 44 , and stimulation of glucagon-like peptide-1 45