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If the fluid cannot drain through this angle, it backs up into the eye itself, causing elevated IOP

Grimminger declares he has been a consultant for Bayer Healthcare, has received speakers bureau (honoraria) from Actelion, Encysive, and Pfizer, and has received grant/research support from Actelion, Excellence Cluster Cardiopulmonary System, GlaxoSmithKlein, German Research Foundation, Novartis, Parexel International GmbH, Pfizer, and the University of Giessen and Marburg Lung Center

& Ylikorkala, O

Conclusion: Overall, this study sheds light on metabolic pathways that are dysregulated in tamoxifen-resistant cell lines and the potential role of each of these pathways in the development of resistance