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Possible Side Effects Mild side effects of Vitamin B12 may include: ( 12 ) Mild pain, itching, or swelling at the injection site Temporary nausea or headache Mild diarrhea Hot flashes Vomiting These side effects do not affect all patients and are generally temporary and mild While rare, more serious side effects of Vitamin B12 injections can include ( 12 ): Irregular heartbeat Heart palpitations Hives or skin rash If you notice any severe reactions to a Vitamin B12 shot, contact a medical professional immediately

If you have two hands and can do it, you can stabilize the needle with one hand or you can just move your finger back and push all the medication in at a slow, steady rate

For people with more subcutaneous tissue If you carry more body fat, particularly in the thighs, you have several advantages

One way of treating anemia is with intravenous iron, or an iron infusion, which is delivered into a vein through a needle to increase the levels of iron and hemoglobin in your body