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Besides, a growing body of evidence shows that glutamate is able to regulate arteriole diameter, blood-brain barrier disruption and vasodilation (Sharp et al., 2003

The antibody-drug conjugate (ADC) successfully targeted MDA-MB-231 tumors in a murine model, leading to a significant decrease in tumor growth compared to untreated mice and mice treated with MMAE conjugated to a non-binding antibody control [83]