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The results indicate that while the radiotherapy group slightly improves LRR, this does not translate into a survival benefit

Nail Abnormalities Psoriasis can also affect nails, leading to thickening, pitting (small depressions on the surface), or ridges

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Unexpectedly, we also revealed that PIN1 can be targeted for degradation by active APC/C CDH1 in a reciprocal mechanism and that combined PIN1 and CDKs inhibition could synergistically and irreversibly activate APC/C CDH1 to induce the robust degradation of PIN1 and other mitotic proteins