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Collectively, these advancements underscore the potential of ferroptosis as a therapeutic target and highlight the importance of integrating innovative technologies to improve outcomes in GBM treatmentHowever, clinical translation faces hurdles, including GBM heterogeneity, the TME, and lack of reliable biomarkers

Some studies have shown that AOD-9604 may regulate the rich acid oxidation process by affecting the activity of specific fatty acid oxidases, such as the activity of mitochondrial glycerophospholipids