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The effectiveness of antibiotics in treating early-stage Lyme disease is well-established, particularly when initiated promptly

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An adequate evaluation of the glutamine hypothesis would be to supply patients with hypoglutaminemia at ICU admission with a dose of glutamine that normalizes plasma glutamine together with an adequate caloric and protein supply, not less than 50 % of energy expenditure and not less than 50 % of ESPEN-recommended protein supply

INF2 has direct connections with energy metabolism in its critical role in regulating mitochondrial stress in a high oxidative stress environment (89)