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The principles of operation of the compounds according to the present invention may be better understood with reference to the drawings and accompanying descriptions

Signs of acute tennis elbow include pain that developed recently following increased activity, tenderness directly over the lateral epicondyle, pain that worsens with resisted wrist extension, and morning stiffness that improves with movement

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Furthermore, subchondral angiogenesis, often driven by VEGF and mechanical stress, disrupts the osteochondral interface and promotes cartilage deterioration (Noh et al., 2020)