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for example, an adult typically contains 1.8 g and 1 g of iron in the blood and liver, respectively, and 2 mg and 100 mg of zinc in the blood and liver, respectively, compared with only 40 g and 1.5 mg of Mn in the blood and liver, respectively 18,19,20

For instance, long-term use of NAC may cause some gastrointestinal reactions, and high doses of vitamin E have been associated with an increased risk of hemorrhagic stroke (Schwalfenberg, 2021)

doi: 10.1134/S0006297920100065 98 KatkarGDSundaramMSNaveenKumarSKSwethakumarBSharmaRDPaulMet al

Funding This research was supported by the National Natural Science Foundation of China (82371382, 81771381), Anhui Provincial Key Research and Development Project (2022e07020030, 2022e07020032), Science Research Project of Bengbu Medical College (2021byfy002), Anhui Province Key Laboratory of Tissue Transplantation (Bengbu Medical College)(AHTT2022B001), and the Undergraduate Innovative Training Program of China (202110367037)