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Available at: fda.gov Rosenfeld RG, et al

Esculetin improved lipid metabolism in FFA-treated primary hepatocytes by decreasing expression of Srebp1c and increasing expression of Ppar- as well as reducing lipid accumulation

Being open about scientific questions is key to gaining trust

The underlying mechanism involves the suppression of the NF-B signaling pathway, which plays a crucial role in inflammation and keratinocyte proliferation associated with PsO