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Furthermore, according to the recent discovery of mtDNA mutations in HLRCC patients [33], it is important to consider potential mutations and alterations in mitochondrial DNA content affecting tumorigenesis in these tumours

Ginsenoside Rh2 can affect the expression of apoptotic proteins such as Bcl-2 in osteosarcoma (U-2 OS) and esophageal cancer (ECA109 and TE-13) cells, thereby inhibiting tumor progression [665, 666]

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