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HGH injections create supraphysiological spikes followed by rapid decline Side effect profiles differ significantly: Published data shows secretagogues have milder side effects (injection site reactions, mild water retention) compared to HGH (joint pain, insulin resistance, potential organ enlargement at high doses) Regulatory status differs: HGH (somatropin) is FDA-approved for specific conditions

Interests quickly aligned and MacKay found himself enrolled in the EMI programme, working with GSK's clinicians and scientists to develop magnetic resonance imaging techniques that can be used as a rapid and non-invasive way of assessing the effectiveness of treatments for osteoarthritis of the knee

2009;49:S138-45.[PubMed Abstract] - 67.Vento S, Di Perri G, Garofano T, Concia E, Bassetti D

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