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Based on the dynamic fluctuations of the vaginal microbiota across the menstrual cycle, a novel temporal classification framework called vaginal community dynamics (VCDs) categorizes community transition patterns into four types: (1) the constant eubiotic, (2) the menses-related dysbiotic, (3) the unstable dysbiotic, which changes community states for a short while, and (4) the constant dysbiotic 74

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For BD patients, serum lithium concentrations must be meticulously maintained within a narrow therapeutic window, typically ranging from 0.4 to 1.0 mmol L 1 , to balance therapeutic efficacy with systemic safety