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This activates the intrinsic pathway via mitochondrial outer membrane permeabilization, releasing cytochrome C and forming the apoptosome complex with apoptotic protease activating factor-1 (Apaf-1) and procaspase-9 (Hashemi et al

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The toxic metal hypothesis is compatible with most features of ALS (Figure 11)

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Physical activity and quality of life in retinitis pigmentosa

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doi: 10.1080/10409238.2017.1409191 48 DuncanJAGilmanAG

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