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doi: 10.1158/0008-5472.CAN-07-1872 78 SommerfeldtLPortillaHJacobsenLGjerstadJWyllerVB

Changes in the brain [NAD(+)]/[NADH] and [NADPH]/[NADP(+)] with aging and anti-aging dietary restriction Frontiers in aging neuroscience

Rapid weight loss can provoke an inflammatory response, increasing the production of pro-inflammatory cytokines

Under this assumption, the simulated the effect of joint L838,417 and CLP257 application is computed by first transforming the dose of CLP257 into a dose of L838,417 yielding an equivalent effect