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The researchers theorized that glutathione depletion may play at least a partial causative role in reduced immune response in people with HIV, and that increasing systemic glutathione could improve immune system function in this group

While many factors influence long-term health, healthy glutathione levels are widely recognised as an important component of overall wellbeing and cellular health

2025 Mar;21(3):371-382

To explore the relevance of GSH to the distinct redox properties of FoB and MZB in vivo, we generated B cell-specific Gclc -deficient mice by crossing Gclc fl/fl mice with Mb1-Cre + mice ( Gclc fl/fl Mb1-Cre + ), in which the Cre recombinase gene is expressed under the control of the B cell-specific promoter Mb1 46