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Thus, here, we showed that exogenous glutathione has the potential to restore the redox status of cardiac mitochondria due to the reduction of oxidative stress, improvement of mtNOS activity and H 2 S levels which leads to the inhibition of mPTP and improvement of the functions of the cardiovascular system in old rats

Following ICH, iron released from hemoglobin triggers excessive ROS production, leading to oxidative stress and secondary brain injury

this suggests that the current estimate of a core of 4,200 genes is too high, and that more genomes are needed to define the core-genome and pan-genome in the Ajellomycetaceae (Figure S6)

& Meininger, C