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Olaparib is a compound that effectively inhibits PARP1 and PARP2, binding to the catalytic domain and preventing the transfer of ADP-ribose units from NAD + to target proteins, thus lowering NAD + consumption 160,161

Glutathione acts as a master antioxidant, detoxifying the body and protecting cells, while Vitamin C and Zinc further strengthen immune defenses and promote cellular health

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To account for the expanded patient cohort and the expected differences in observed costs, the measure is stratified into three sub-groups based on diagnosis and each sub-group uses a separate risk adjustment model