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Miller NA, Reddy MB, Heikkinen AT, Lukacova V, Parrott N (2019) Physiologically based Pharmacokinetic modelling for First-In-Human predictions: an updated model Building strategy illustrated with challenging industry case studies

We recognize the importance of maximizing therapeutic effectiveness, and injectable Toradol helps us achieve higher blood concentrations and more immediate pain relief

Bringmann G (1973) [Determination of biological hazards of water polluting substances from the inhibition of glucose assimilation of the bacterium Pseudomonas fluorescens

This demands a dosing strategy focused on mass and sustained concentration (e.g., loading doses and frequent injections to maintain a therapeutic plateau)