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40, 41 At one time it was thought that any solution which will not produce a slough when injected perivenously will generally not be strong enough to obliterate a vein. 42 However, some very effective sclerosing solutions are thought to act selectively on damaged varicose endothelium

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Human proteinderived peptides with strong membrane-permeating properties were screened, and the candidate demonstrating the greatest proliferative effect on dermal papilla cells and highest induction of hair growthrelated proteins was selected

Interestingly, the endocytosed BDNF can be further modified by the recipient cell before the re-release event