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The sex difference in serine-312 phosphorylation of IRS-1 (pSer-IRS-1) may be akin of an increased vulnerability and a more advanced stage of brain IR in women than men with MDD

Kidney function highly depends of the homeostasis of this organelle, and mitochondria play a hub in signaling pathways, metabolic regulation, calcium homeostasis, and inflammation through the redox regulation, which also is important for the feedback communication with other organelles like endoplasmic reticulum (ER) and peroxisomes (MartnezKlimova et al