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Description

Desferrioxamine mesylate for managing transfusional iron overload in people with transfusion-dependent thalassaemia

The RRP consists of a small fraction of total vesicles that are physically docked at the active zone, molecularly primed by active zone proteins (such as RIM and Munc13) into a SNARE-assembled, fusion-competent state (Kaeser and Regehr, 2017)

A phase 3 double-blind, double-dummy, randomised controlled trial (RCT) comparing IPX203 with immediate-release (IR) LD/CD showed a statistically significantly greater increase in daily ON-time of + 0.53 h, and this difference was achieved with a mean of 3 daily doses vs 5 in the IR LD/CD arm [22]

By utilizing liposomal delivery to flood the body with intact, ready-to-use glutathione, we can take the metabolic burden off these exhausted immune cells