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We dont have long-term safety data

If those mutations occur in a gene important to cancer prevention, then a tumor can occur.[ref] Thus, folate helps to prevent the mutations that cause cancer, yet in someone who has cancer, folate and methyl groups can fuel cancer cell growth

Creatine supplementation improves muscle strength and function, potentially averting functional disability in older adults

A study published in the Journal of Orthopaedic & Physical Therapy (2017) found that treating flat feet by focusing on hip and pelvic alignment significantly improved foot mechanics and reduced symptoms of plantar fasciitis