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Description

These molecules stimulate NF-B activity either directly or through cytokine-mediated expression

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Under normal physiological conditions, Keap1, as the substrate adaptor of the E3 ubiquitin ligase complex, maintains intracellular redox balance by promoting the ubiquitination and degradation of Nrf2