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All inhibitors had relatively similar binding free energy (G Bind ) values ranging from 43.17 to 33.64 kcal/mol

Referencer: Kim et al

This conversion process may be hampered in patients with PCOS due to decreased aromatase activity in ovarian granulosa cells, which could result in intraovarian androgen buildup, maintaining the PCOS phenotype by aggravating ovulatory failure and hyperandrogenism (Yu et al., 2013)

Figure 1 The antioxidant resveratrol repressed SRY-box 2, blocked AKT, and inhibited signal transducer and activator of transcription 3 signalling, among other effects