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This is mediated via TGF-1 upregulation and results in peritoneal EMT (Yang et al., 2017)

It plays an important role not just in the male sex drive but in red blood cell production, sperm production, body mass, body fat, muscle mass, muscle strength, and more

Vitamins D3, K2, and niacin inhibit iNOS activity in the neuronal cells (macrophage, microglia, and astrocytes) Lipid peroxidation of the membrane is prevented by vitamin E as it inhibits the ROS generation

ROS has also been shown to increase the expression of TGF-1 signalling, with downstream effects including elevated expression of collagen, fibronectin, bFGF, and matrix production 104,137