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Zhou, Y, Xu, ZZ, He, Y, Yang, Y, Liu, L, Lin, Q, et al

It is likely that all main isoenzymes present in the choroidal tissue during the early developmental period, namely GST mu1&2, GST alpha3&4, GST pi1 are sensitive to Nrf2 activation, as these isoenzymes are upregulated by inducers of the Nrf2 signaling pathway in the liver of adult rats [32]

As of mid-2026, no published human clinical trials exist for the compound

They modulate intestinal tissue dendritic cells to produce IL-10, decrease IFN- release by intestinal T-cells and decrease LPS-induced production of the proinflammatory IL-12 [119]