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cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the Aryl hydrocarbon receptor nuclear translocator (Arnt)

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This study included 92 people with ME/CFS and 44 sedentary healthy controls and found lower baseline irisin levels and blunted exertional response in people with ME/CFS