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CR impacts mitochondrial function and energy metabolism by upregulating superoxide dismutase 2 and activating the AMPK/silent information regulator sirtuin 1/Peroxisome proliferator-activated receptor-gamma coactivator-1 alpha signaling pathway (Vo et al

Kahle PJ, Waak J, Gasser T

The good news is that human research on the metabolic and longevity aspects of intermittent fasting is burgeoning as of late, and preliminary evidence is generally promising

This is consistent with the fact that examination of the fatty-acid oxidation pathway in fibroblast culture did not reveal any abnormalities to explain the elevations in acyl-carnitines