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cocaine and melanotan Pyoderma Gangrenosum Secondary to Synaptic changes induced by melanocortin

Name: cocaine and melanotan Pyoderma Gangrenosum Secondary to Synaptic changes induced by melanocortin
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Dehydroascorbic acid, a blood brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke

Compared with unipolar depression, bipolar depressed subjects had significantly decreased connectivity between pgACC and amygdala and dorsomedial thalamus (150) Moreover, a separate group of investigators reported a more intense activation of ventral striatal, thalamic, hippocampal, amygdala, caudate nucleus/putamen, vmPFC, ventrolateral PFC, and ACC in bipolar depressed individuals compared with MDD and a healthy control group, especially in response to mildly and intensely fearful and sad, and mildly happy expressions (104)