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Description

IUBMB Life 63 , 538546 (2011)

PrfA* mutants contain a G145S mutation in the virulence regulator PrfA that results in constitutive virulence gene expression, including upregulation of uhpT for the use of hexose phosphates [2325]

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Things like antibiotics, ongoing stress, poor sleep, illness, hormone changes, high sugar intake, immune stress, and shifts in gut bacteria can all play a part