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Psoriasis disease and medical history characteristics included psoriasis disease duration, history of psoriasis in a difficult-to-treat area (scalp, genitals, nails, palms and soles, or inverse/intertriginous areas), history of non-plaque psoriasis (guttate, erythrodermic, or pustular), and the number of previous topical therapies used (corticosteroids, tacrolimus, pimecrolimus, calcipotriene/calcitriol, vitamin D 3 analogue/steroid combination, tar, anthralin, tazarotene, roflumilast, or tapinarof)

If a peptide is ultimately added to the FDA's 503A Bulks List following the agency's review and rulemaking process, licensed 503A pharmacies may be permitted to compound it from bulk active pharmaceutical ingredients (APIs), where appropriate

This shift in priorities is driving renewed interest in amylin-based therapies, particularly Petrelintide, a once-weekly long-acting amylin analog currently under investigation

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