hplc glutathione Optimisation of conjugation to liposomes quantified with a validated assay a) Total glutathione (GSH) content

doi: 10.1007/s11033-024-09737-6 109 KhounganianRAudaSAl-ZaqzouqRAl-SemariHShakeelF

A., Kowluru, V., Xiong, Y

These effects may potentially provide a novel therapeutic solution for stroke, imparting specific beneficial effects on the CNS (i.e., for reperfusion, the amelioration of neuronal damage and, thereby, recovery without memory, locomotor, and coordination disturbances, and the expression of the particular genes in the hippocampus)

After verifying the low levels of GSH in brain, 2D electrophoresis was performed to detect oxidized protein carbonyls which further confirm GCL knockdown causes protein oxidation in vivo