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[DOI] [PubMed] [Google Scholar] 86.Zrelli H, Matsuoka M, Kitazaki S, Zarrouk M, Miyazaki H

Peroxynitrite inactivation of tyrosine hydroxylase: mediation by sulfhydryl oxidation, not tyrosine nitration

This helps prevent these types of issues

If a dose is missed, patients could apply it when remembered on the same day or resume the regular schedule at the next planned administration-double dosing is not recommended