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However, when allopurinol is administered, the urinary output is composed of hypoxanthine, xanthine and some amounts of uric acid, thereby reducing the risk of crystalluria, a condition characterized by the presence of uric acid crystals in urine, nephrolithiasis, nephrocalcinosis, and sometimes, acute or chronic kidney impairment (80)

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ZhangHPWangYHMaSCZhangHYangANYangXLet alHomocysteine inhibits endothelial progenitor cells proliferation via DNMT1-mediated hypomethylation of Cyclin A

Similar phenomena also occur in many other types of cancers treated with cisplatin [pancreatic cancer, lung cancer (LC) and breast cancer (BC)], which indicates that inhibition of FAO may counter resistance to cisplatin in a variety of cancers [50]

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