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3068-A DIASTOLIC DYSFUNCTION IN CIRRHOTIC CARDIOMYOPATHY: A PROSPECTIVE OBSERVATIONAL COHORT STUDY ON SHORT-TERM OUTCOMES IN CIRRHOTIC PATIENTS UNDERGOING TIPS Yaozu Liu 1,2,3 , Fangmin Meng 1,4 , Wen Zhang 1,2,3 , Jingqin Ma 1,2,3 , Zhiping Yan 1,2,3 , Cuizhen Pan 1,4 and Jianjun Luo 1,2,3,5 , (1)Shanghai Institute of Medical Imaging, (2)Department of Interventional Radiology, Zhongshan Hospital, Fudan University, (3)National Clinical Research Centre for Interventional Medicine, Zhongshan Hospital, Fudan University, (4)Department of Echocardiography, Zhongshan Hospital, Fudan University, (5)Centre for Tumor Diagnosis and Therapy, Jinshan Hospital, Fudan University Background: The placement of Transjugular intrahepatic portosystemic shunt (TIPS) results in a sudden increase in central circulating blood volume, which requires proper regulation of the cardiovascular system

The inhibitory constant for NAM in various sirtuin enzymes has been determined to be in the range of 30200 M

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