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In skeletal muscle specifically, MOTS-c has been shown to enhance glucose transporter-4 (GLUT4) translocation to the cell surface, the molecular mechanism by which muscle cells absorb glucose from the bloodstream

This work was supported by grants of the European Union, the European Regional Development Fund, the Free State of Saxony within the framework of the excellence initiative, the LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig (project numbers: 713-241202, 14505/2470, 14575/2470), and funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germanys Excellence Strategy EXC-3105/1 533765739, and by the Federal Ministry of Research, Technology and Space (Bundesmin- isterium fr Forschung, Technologie und Raumfahrt