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10 Microbiome and gut-ovary axis The pathophysiology of PCOS is now understood to be significantly influenced by the complex interaction between the gut microbiota and the ovaries, known as the gut-ovary axis (80)

Scientific investigations have emphasized the promise of GlyT1 inhibition as a treatment strategy, particularly Org 24,598, in mitigating substance abuse, with preclinical studies demonstrating its anti-addictive properties in multiple addiction paradigms