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Treadmill running (10 m/min, 5 days/week for 6 weeks) increases dopamine D2 receptor-like binding in the dorsomedial caudate putamen, ventrolateral caudate putamen, ventromedial caudate putamen, and olfactory tubercle, supporting its potential antidepressant effects [106]

By approaching it with curiosity and a commitment to precision, you can eliminate the discomfort and ensure that your research protocol is as clean, consistent, and reliable as the high-purity compounds you're working with

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Since in most of the studies the participants were not masked to the intervention, and they reported the outcomes which were subjective, even if the assessors were blind to the intervention, the measurement of the outcome domain was at high risk of bias