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10.1016/0024-3205(85)90146-8 158 NicolettiA.PuglieseP.NicolettiG.ArabiaG.AnnesiG.MariM

Inflammaging and oxidative stress in human diseases: from molecular mechanisms to novel treatments

ZaricBLRadovanovicJNGluvicZStewartAJEssackMMotwalliOet alAtherosclerosis linked to aberrant amino acid metabolism and immunosuppressive amino acid catabolizing enzymes

Further research has shown that TPC2 counterbalances OCA2, a positive regulator of pigmentation, by increasing the melanosomal membrane potential to decrease melanin content