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Description

111 Non-clinical data reported to date have provided evidence for potent and highly specific on-target editing of the ANGPTL3 gene in primary human hepatocytes

Anti-inflammatory activity Cell culture Murine macrophage RAW264.7 cell were cultured in Modified Eagles Medium (DMEM) (Gibco, Grand Island, NY, USA) supplemented with 10% heat-inactivated fetal bovine serum (FBS) and 1% penicillin-streptomycin (100 U/mL penicillin and 100 g/mL streptomycin) under humidified condition with 5% CO2 at 37 C