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In summary, oral administration of iron chelators (especially DFP) provides a non-invasive and promising dosing route for treating brain iron accumulation, but it requires prolonged treatment to achieve effective concentrations, close safety monitoring due to chronic treatment at relatively large dose, and its efficacy might be constrained by peripheral iron binding and the need for sufficient BBB penetration

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Theoretically, reducing systemic inflammation could enhance metabolic outcomes

After completing a nutrigenomic test, Liz discovered that she (like one third of the population) lacks the gene expression needed to convert nutrients from food into glutathione