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Back to top TRIALS ON GSH In a clinical trial Italy in 1992, 11 infertile men were treated with glutathione (600 mg/day IM) for 2 months

This is consistent with PTGIRs known function as a suppressor of intracellular cAMP signaling in platelets and smooth muscle cells 33 , which impairs DNA binding of SREBP2, a key transcription factor controlling cholesterol homeostasis 34