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Description

J Orthop Surg Res 19 , 759 (2024)

Note: Originally published in 2016, this article has been updated for accuracy and thoroughness.

Once in the central nervous system (CNS), the virus can either reside in a quiescent latent state in this tissue, or eventually actively lead to severe acute necrotizing encephalitis, which is characterized by exacerbated neuroinflammation and prolonged neuroimmune activation producing a life-threatening disease