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We focus on the "Neuro-Inflammatory" model of depression and anxiety

10.1016/j.mehy.2006.02.040 Med

Although the HBD of SOD3 does not participate in the enzymatic activity of SOD3, its HBD region is required for binding to type I collagen and LDL receptor-associated proteins, which are absorbed and internalized into cells via adhesion proteins and low-density protein receptor-associated proteins (LRP)-mediated endocytosis pathways