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PMID: 30400267

Specifically, the effective mass of electrons ( m e * ) and holes ( m h * ) can be calculated using either the curvature approximation of the parabolic band structure or a numerical fitting approach [67]

Individuals who have deletions of the entire NF1 gene have an increased risk of facial dysmorphism, mental retardation, early appearance of neurofibromas, and the presence of plexiform neurofibromas.1 In addition, individuals who have a specific 3 base pair in-frame deletion in exon 17 of the NF1 gene may have caf-au-lait spots, intertriginous freckling and Lisch nodules, but do not develop cutaneous, subcutaneous or plexiform neurofibromas

In RA, reduced mitochondrial DNA biostability and mtDNA leakage into the cytoplasm due to the lack of DNA repair nuclease (MRE11A) increase the pro-inflammatory tendency of T-cells, whereas upregulation of MRE11A expression reduces mitochondrial damage and has an inhibitory effect on T-cell scorching and immune inflammation (75)