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2021;9(11): e003254

OSBORNE, A.D., PITTS, J.N., & DARLEY, E.F

Their mode of action can be paracrine (acting on neighboring cells), autocrine (activating receptors on the cells that synthesized them), or endocrine (acting at a distance, via the circulation) 25 (Fig

In some experiments, mice were processed for immunocytochemistry (see below) two hours after ip IGF-I injection to allow expression of c-fos, whereas in other experiments PeF recordings were carried out immediately after ip injection