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Description

D.et al (2003a)

Villar VH, Nguyen TL, Delcroix V, Ters S, Bouchecareilh M, Salin B, et al

Basal cell cycle distribution has been implicated in the radio response, with cells in the S phase and G0/G1 phases being more radioresistant, and cells in the G2/M phase being the most sensitive to radiation exposure ( Metformin treatment significantly reduced the proportion of radiosensitive HCT116 cells in the G0/G1 phase at 48 h post treatment, when compared to vehicle control ( Figure 2A )