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Front Med (Lausanne) 7:563020 Timsit J, Riou B, Bertherat J, Wisnewsky C, Kato NS, Weisberg AS, Lubetzki J, Lecarpentier Y, Winegrad S, Mercadier JJ (1990) Effects of chronic growth hormone hypersecretion on intrinsic contractility, energetics, isomyosin pattern, and myosin adenosine triphosphatase activity of rat left ventricle

In parallel, increases in level of T- MCA, an intestinal FXR antagonist, ameliorates NAFLD through increased BAs synthesis [135,136,137], and GLP-1 secretion decreases via the activation of intestinal FXR [138]

185,204 Importantly, the inclusion of some progestins in postmenopausal hormone therapy has been linked to increased breast cancer risk and may reverse the cardioprotective benefits of estrogen therapy