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This pathway plays a minor role in regulating levels of methemoglobinemia

doi: 10.1016/j.nbd.2025.106967 147 PosthumusTBEngelkeUFHAspersRMerxJBoltjeTJMartensJet al

pmid:1377674 18

This dysregulation exerts dual biological effects: ACSL4 enhances fatty acid accumulation by modulating lipid metabolism regulators (e.g., c-Myc and sterol regulatory element-binding proteins, SREBPs) to drive MM proliferation (Zhang et al., 2023)